I finally think I tracked this down. When I looked deeper at the error I got from /api/v2/system/environment, I noticed that there was a reference to /opt/bitnami/apps/dreamfactory/htdocs/storage/framework/cache. When I went to that directory, I discovered that some of the subdirectories of that folder had root:root permissions. I ran sudo chown -R daemon:daemon * and lo and behold the site fired back up. I’m not sure what created the root:root permissions.
I’ll continue to monitor as I test and see if it comes back or if it was a problem with the bitnami image to start with.